منابع مشابه
Hypersensitive substrate for ribonucleases.
A substrate for a hypersensitive assay of ribonucleolytic activity was developed in a systematic manner. This substrate is based on the fluorescence quenching of fluorescein held in proximity to rhodamine by a single ribonucleotide embedded within a series of deoxynucleotides. When the substrate is cleaved, the fluorescence of fluorescein is manifested. The optimal substrate is a tetranucleotid...
متن کاملRibonucleases and bacterial virulence
Bacterial stress responses provide them the opportunity to survive hostile environments, proliferate and potentially cause diseases in humans and animals. The way in which pathogenic bacteria interact with host immune cells triggers a complicated series of events that include rapid genetic re-programming in response to the various host conditions encountered. Viewed in this light, the bacterial...
متن کاملRibonucleases in tumor growth.
This review summarizes data on ambiguous biological functions of ribonucleases (RNases) at tumor growth. In some cases the raised level of enzyme activity in biological fluids can be regarded as an additional marker of malignant growth (pancreas cancer, chronic myeloid leukemia, etc.). At the same time the activity of RNases is often lowered in tumor tissue. High substrate specificity of partic...
متن کاملRibonucleases and angiogenins from fish.
For the first time fish RNases have been isolated and characterized. Their functional and structural properties indicate that they belong to the RNase A superfamily (or tetrapod RNase superfamily), now more appropriately described as the vertebrate RNase superfamily. Our findings suggest why previously repeated efforts to isolate RNases from fish tissues have met with no success; fish RNases ha...
متن کاملCan DNA Topoisomerases Be Ribonucleases?
(59-OH). Although this covalent intermediate is chemically very stable, the steady-state concentration of this intermediate is usually low. This is because the ligation Alex B. Burgin, Jr. Biology Department San Diego State University San Diego, California 92182-4614 reaction is faster than the cleavage reaction. During ligation, the 59-OH generated during cleavage displaces the covalent DNA–en...
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ژورنال
عنوان ژورنال: Acta Societatis Botanicorum Poloniae
سال: 2015
ISSN: 2083-9480
DOI: 10.5586/asbp.1964.055